Finasteride-associated male infertility

Case Report Finasteride-associated Male Infertility

Finasteride is a potent and specific inhibitor of the 5α-reductase enzyme in men. Clinical studies have shown that finasteride 1mg/day is effective for promoting hair growth in men with male pattern hair loss. However, there is a concern about the use of finasteride, especially in young fertile patients, because of its action on testosterone metabolism. This paper describes 3 cases of young pat...

Gene Mutations Associated with Male Infertility

Imprisonment-associated sperm clumping and male infertility.

OBJECTIVE This observational, retrospective study investigated infertility among Iraqi men who had been long-term prisoners of war. METHODS Routine seminal fluid analyses were undertaken in former prisoners with suspected infertility attending the Ramadi Infertility Clinic, Ramadi, Iraq; semen samples were also microscopically evaluated in these patients. RESULTS In 16 out of 38 patients (...

ACUPUNCTURE AND MALE INFERTILITY About male infertility

The clinical definition of male infertility is the presence of abnormal semen parameters in the male partner of a couple who have been unable to conceive after 1 year of unprotected intercourse (Dohle 2010). The World Health Organization defines male factor infertility as the presence of one or more abnormalities in the semen analysis, or the presence of inadequate sexual or ejaculatory functio...

Male breast cancer during finasteride therapy.

Male breast cancer is an uncommon disease, with an estimated incidence of one case per 100 000 man-years (1). Conditions that result in relative estrogen excess or lack of androgen are associated with an increased risk of breast cancer in both women (2) and men (3). An example of increased rates of male breast cancer associated with increased estrogen-to-testosterone ratios can be seen in men w...